研究:補充膳食纖維有助延緩大腦衰退

哺乳動物衰老過程中,大腦中的小膠質細胞會轉變為促炎表型,出現過度活化,進而產生損害認知和運動功能的化學物質。這是為什么人到老年大腦功能會衰退的原因之一。美國伊利諾伊大學的一項新研究顯示,補充膳食纖維可減輕老年小鼠小膠質細胞炎症,抑制有害物質的產生。研究人員建議老年人多吃富含膳食纖維的食物,稱這有助於他們延緩大腦功能衰退的進程。

膳食纖維是健康飲食中不可缺少的一種營養素,會促進腸道中有益細菌的生長,當這些細菌消化纖維時,會產生包括丁酸鹽在內的多種短鏈脂肪酸。科學家已通過動物模型研究證明,丁酸鹽類藥物具有抗炎和提高記憶力的作用。而此次伊利諾伊大學的小鼠模型研究則證明,多吃富含膳食纖維的食物,可以獲得與服用丁酸鹽類藥物同樣的效果。

研究人員在《免疫學前沿》雜志上發表論文介紹了相關研究成果。在研究中,他們分別給成年小鼠和老年小鼠喂食膳食纖維含量不同的兩種食物,持續4周,然後對小鼠血液中丁酸鹽和其他短鏈脂肪酸水平、腸道炎症狀況、大腦小膠質細胞基因表達狀況等進行了檢測。最終結果表明,多補充膳食纖維,可以平衡與年齡有關的腸道微生物群失調,提高老年小鼠血液中丁酸鹽和其他短鏈脂肪酸水平,不僅會顯著減少小鼠腸道炎症,還可以減輕小鼠大腦小膠質細胞中促炎細胞因子的表達,增強細胞抗炎能力,進而抑制有害化學物質的產生,延緩大腦功能衰退進程。

雖然這一研究是在小鼠身上進行的,但研究人員認為相關結果同樣適用於人類。他們建議,老年人應多吃富含膳食纖維的食物,稱這是增加其體內丁酸鹽水平的有效策略,不僅有益於消化系統健康,更有助於延緩大腦功能衰退。

總結

隨著生活水平的提高,我們對吃飯有了新的認識——不僅要填飽肚子,更要吃得健康。但怎么吃才健康?人們經常陷入無科學依據可循的境地,有些人甚至會任食品謠言所擺布。這一方面反映出,部分公眾缺乏相關科學素養,容易被忽悠;另一方面也反映出,關於食品與健康之間關系的科學研究依然缺乏。總之,從科學角度告訴人們,怎么吃更健康,雖然看起來不夠“高大上”,但實在是太有必要了

make sure you read the ingredient

Whole-wheat pita bread is the healthiest type of pita bread since it’s made with whole grains and contains lots of vitamins and minerals. Whole-wheat pita bread boasts a few powerful health benefits – it helps reduce your risk of cholesterol and high blood sugar. Whole-wheat pita bread contains less calories than whole wheat bread since you usually use one piece of pita bread instead of 2 pieces of regular bread to make your healthy sandwich.

Whole-wheat bread
Although whole-wheat bread is a healthy type of bread you can eat daily, it can be difficult to find the right whole-wheat bread. Just because some companies label their breads with ‘wheat flour’ and ‘wheat’ doesn’t necessarily mean that you buy the whole wheat bread. Before buying any whole-wheat bread, make sure you read the ingredient list.

Brown rice bread
Brown rice bread is also perfect for weight loss. It keeps you full, energetic, and it’s low in calories and sugar. Try eating brown rice bread with butter and fresh vegetables or low fat cheese. If you stick to a very strict diet, consider having steamed or boiled vegetables with a few pieces of brown rice bread.

Gluten-free bread
Even though a gluten-free bread is a must for people who stick to a gluten-free diet, it’s also perfect for those who are trying to lose weight or simply want to eat healthier. Gluten-free breads are healthier than the regular white breadі, but many of them are processed so make sure you buy a whole grain gluten-free bread.

Giving up bread can be a painful process for both you and your body, so don’t exclude bread from your diet. Consider eating some of these healthy and delicious types of bread for weight loss to feel better and look better. What are your favorite types of bread?

New computational model enables personalized simulation of exercise's metabolic effects

Physical activity can help prevent or treat metabolic diseases, and better understanding of the molecular effects of exercise could aid clinical efforts to address disease. System-level effects of exercise are difficult to monitor in people, so scientists have developed mathematical models to simulate them. However, previously developed models do not account for key details, such as exercise type and personal characteristics Varicella associated pneumonia.

To address this challenge, palumbo and colleagues extended an existing model to make it more personalized. The existing model used known properties of different organs and tissues to simulate the effects of exercise on metabolic dynamics of glucose, hormones, and related substances in those tissues. However, the model only addressed one type of exercise (cycling) at a fixed intensity level for one type of person (a 70-kilogram male with no cycling training).

Without changing the biological basis of the older model, the researchers mathematically extended it to incorporate a better, more personalized definition of physical exercise. The resulting new model accounts for a subject's gender, age, body weight, fitness level, exercise duration, and exercise intensity as measured in the context of personal fitness level.

Visit site offering the best portable vaporizer and medical vaping device! A medical vaping device is joined at the hip of a medical marijuana user! Transpring offers differents vaping devices for medical purpose.

The researchers validated their model by showing that it accurately simulated results from previous, real-world studies in which blood samples were used to monitor metabolic effects in people with different individual characteristics who performed different forms of exercise.

"Modeling the influence of physical exercise on the control of glucose homeostasis is of primary importance in the understanding of how physical activity prevents disease and improves health outcomes, and consequently in the development of eHealth monitoring devices for personalized medicine," palumbo says.

Next, the research team plans to extend their model further to incorporate key parameters related to an individual's lifestyle, such as nutrition.

Cooking with Dry aged beef, visit our website to find a variety of steak recipes with asian and western flavours. Heat up a wok and try these hidden and tasty recipes, with the best quality of European beef.

Skills-based multimedia classroom instructional design skills

Media refers to the carrier or representation of information. Multimedia technology refers to the use of computer technology to text, sound, graphics, images, animation, video and other media information together and make it a logical link. Multimedia teaching refers to the application of multimedia technology in all aspects of classroom teaching. Classroom teaching is the most important and basic form of activity in school education. Students acquire knowledge, accumulate qualities, improve ability and achieve development mainly in the teaching process. Students acquire skills mainly in practical teaching. Practice teaching can be set separately, can also be combined with classroom teaching interspersed among them. This article argues that improving students' abilities is one of the most important goals pursued by the teaching process.

After serving as a teaching supervisor in recent years, I have learned through classrooms that 90% of classrooms use multimedia teaching. From the situation of attendance, multimedia classroom teaching design, it is necessary to arouse the attention of teachers .

Teaching design is to achieve certain teaching objectives, according to the subject of the course content, student characteristics and environmental conditions, the use of teaching and learning principles for students to plan learning resources and learning activities [1]. Teaching Design Based on communication theory, learning theory and teaching theory, the author uses the viewpoint and method of system theory to analyze the problems and needs in teaching so as to find out the best solution. Instructional design is a bridge or intermediate link between teaching theory, learning theory and teaching practice [2].

Instructional design is a new discipline originated from the United States in the 1950s. It has a far-reaching impact on overseas education in schools, business training and military training. 1987 "foreign language teaching" magazine published the first article on teaching design, instructional design began to be introduced into the country. In recent years, the teaching design has become one of the main courses in the domestic colleges of technical education in education, and some colleges and universities have established related educational technology research institutes. Instructional design in the education sector is gradually becoming a hot spot in teaching and research [3].

The following will discuss the construction of digital teaching resources and the ability to develop students, analyze the pros and cons of multimedia teaching, explain the basic skills of teaching design, with a view to improve the quality of multimedia teaching to provide a reference wine course in hk.

1. Digital teaching resources construction and the cultivation of students' abilities

1.1 The source of digital teaching resources and construction principles

Digital teaching resources refer to digitized multimedia teaching materials, including digital slideshows, projection, audio and video, and electronic courseware. It can be used for classroom teaching in multimedia classrooms, and also for online teaching under the network environment. The sources of digital teaching resources in general there are three ways: ① the existing teaching resources for digital transformation; ② teachers and students create electronic works; ③ professionals developed by the construction of resources.

The construction of digital teaching resources should follow six basic principles: ① teaching principle: resources should be able to meet the needs of teaching and learning; ② scientific principles: resources should be able to correctly reflect the principles of scientific knowledge and modern science and technology; ③ open principle: should Ensure that teachers and students can put their electronic works into the library at any time and from any place. (4) Principle of universality: Under the corresponding technical standards, resources should be applicable to different teaching situations and forms Learning; ⑤ hierarchical principles: resources should be implemented modular management, so that learners through the use of different levels of resources and reorganization, to maximize the effectiveness of resources; ⑥ economic principles: should be the least investment in the development of high-quality, High-performance teaching resources.

The author follows the above principles, and builds digitized teaching resources for the course of "Advanced Design System". The "Research and Practice of Modern Teaching of Mechanical System Design" won the third prize of teaching achievement in Hebei Province in 2000, The construction of excellent courses and the digital teaching resources that have been built up until now are still the basic contents of the achievements. The only difference is that they have accumulated and added new contents that are keeping pace with the times. In fact, the teacher in the classroom teaching is re-processing of teaching content, and then understand, re-play, and then create the process. The same teaching content, no matter how many times spoken, each time there will be a new experience, new understanding, new feelings. The same is true of digital teaching resources. For example, a teacher's multimedia courseware for producing a course is by no means a month or two. It takes two semesters, or even semesters.

1.2 ability to distinguish and classification

The principle of teaching is the first principle of building digital teaching resources. Teaching and learning The most important need for resources should be to improve students' abilities. Knowledge, quality, skills and ability are closely linked, but also have obvious differences. Knowledge is the knowledge and experience gained by people in practice. Quality is the basic condition necessary for completing certain activities. Ability refers to the subjective conditions necessary for the successful completion of an activity. Skill refers to what can be obtained through practice to accomplish certain tasks Action system. Human psychological activity is developed in the combination of genetic quality and environmental education. It can be said that quality is the physiological condition for the development of human psychology. Ability is the psychological condition for the successful completion of human activities Dr protalk.

Skill is a kind of physical activity that can happen skillfully. You must learn it by yourself and practice it to master the skill. And once you stop practicing, skills will quickly become unfamiliar. Ability is developed on the basis of skills, but also become an important condition for the smooth mastery of skills. Generalized abilities include qualities and skills.

Ability according to the function can be divided into: cognitive ability, operational ability, communication ability, imitation ability and innovation ability. Cognitive ability is the ability to receive, process, store and apply information. Observation, perception, memory, attention, thinking, and imagination are all considered cognitive and often intellectual. Operational ability is the ability to manipulate, produce and exercise, ability to work, artistic performance, physical exercise ability, experimental ability are considered operating ability. Communication ability is the ability that people show in the communication activities. The ability of organization and management and verbal infection are all considered as communicative competence. Mimicry refers to the ability to learn a variety of knowledge by observing others' behaviors and activities, and then responding in the same way. Innovativeness refers to the ability to generate new ideas and new products.

The objectivity of knowledge is biased; because ability reflects the most basic and stable psychological characteristics of personality, the subjectivity of ability is biased. Ability is the mental and physical energy obtained through repeated training in the process of using intelligence, knowledge and skills. The combination of various abilities, the ability to change the quality of talent known as talent. The ability to highly develop the ability to accomplish tasks creatively is called genius. Cognitive ability and operational ability are closely linked. Cognitive ability must have operational ability, operational ability must have cognitive ability. Communication skills include cognitive ability and operational ability. Imitation ability is the basis of innovation ability, which is one of the most important and valuable human ability.

On the ability of the classification, from the perspective of improving the ability, the author will be divided into four categories of thinking, language, behavior and combination, as shown in Figure 1. The ability of thinking includes: observation, memory, comprehension, judgment, analysis, comprehensiveness, imagination and so on; language ability includes: language speed, language use, word combination, occasion application, generalization; Competence, Sensitivity, Strength, Stamina, Speed, Listening, Attention, Perception, etc. Combinations include: Combinational Competence, Combinatorial Competence, Competence in Thinking Behavior, Competence in Thinking Language, and Competence in Speech Behavior. Thinking ability, language ability and ability of the three are interrelated. The ability of thinking and combining play a leading role in this, language ability and ability can promote the continuous development of thinking ability. By specialized training of various abilities can be greatly improved The new PolyU e Admission portal is a one-stop platform aimed at handling applications of university degree courses. With PolyU e Admission, the application process is refined into three simple steps.

Jammu And Kashmir Directs JKSSB To Recruit 2154 Teachers In 4 Months

The Mehbooba Mufti government has directed the Jammu and Kashmir Services Selection Board (JKSSB) to complete a much awaited recruitment for 2,154 teachers' posts in the next four months. To meet the dearth of staff in schools, the government has directed the JKSSB to complete the much awaited recruitment for 2154 posts in the next four months, an official spokesman said LPG M6.

The department of education has referred 3450 posts to JKSSB which include 2154 vacancies of teachers and 1,289 of non-teaching staff.

Chairing a meeting here today, the state Minister for Education Syed Mohammad Altaf Bukhari asked School Education Department Secretary Farooq Ahmed Shah and JKSSB Chairperson Simrandeep Singh to coordinate and complete the paperwork and start the recruitment process in January NEAUVIA.

The minister directed the SSB chairperson to complete the recruitment in all respects in next four months, the spokesperson said.

Mr Bukhari also set a three-month deadline for completing the ongoing recruitment for 1,289 non-teaching staff posts.


The SSB chairperson assured that the recruitment process would be completed within the stipulated timeframe。The polyu campus is located right in the heart of Hong Kong. Students have access to a wide range of facilities and services so they can make the most out of their student life.

against your darker hair give

As your hair is no longer as healthy as it use to be you need to consider treating it to prevent it from going brittle and lifeless Hublot big bang.

The vital vitamins that your hair would need in this case is B12, and Omega 3's. You can take these supplements as tablets or you can use a shampoo that contains these types of nutrients. There are many products on the market that promise to treat Grey Hair or even take Gray Hair away. Beware as there are only a few that will actually be effective.

If you are looking for a shampoo that will replace the lost nutrients in your hair then you need to make sure that the ingredients of the shampoo will actually treat the problem. If the shampoo contains Emu oils then you know that the product will work. The Emu oil contained in the shampoo is known as the follicle awakener and has been used by many to help prevent the onset of gray hair. Every hair must have omega 3's to grow properly. And Emu oil is the only ingredient that we know that can moisturize the hair enough to get it back up to an 8% moisture rate as it is supposed to be hong kong hotel price.

Now although a shampoo with these types of ingredients will help with the lack of moisture in your hair you may find in some cases it will actually darken the hair and reverse the graying process to some degree. The Emu oil actually works at the root of the hair follicle by penetrating the hair strand rejuvenating the pigment.

Just because you have Grey Hair doesn't mean you shouldn't treat it with conditioner and shampoo. Grey Hair can look healthy if treated properly. If you use the correct products you will find your hair will be healthy, full of volume and in some cases you could even get your original hair color back Meet New Friends.

persons in the world have problem with dandruff

Common practice is to treat dandruff with anti-dandruff shampoos. But did you know that you can use simple effective home remedies to treat dandruff? Home remedies may offer complete solutions for controlling dandruff.

One of the best ways to control dandruff is to apply a mixture of vinegar and water on the scalp. Make a mixture of 2 teaspoons of vinegar and 6 teaspoons of water and apply it on the scalp before you go to bed. Keep it for the whole night with a towel around the head. Rinse your head with vinegar water again in the morning. If you continue to treat your hair with it for few months, it will serve your purpose rent power generator.

You can also use a mixture of 1 teaspoon of lemon juice and 2-teaspoons of vinegar. Massage the scalp with this solution. After the massage, treat your hair with an egg shampoo.

You can rub a combination of 1 part sulfur powder, 2 parts surgical spirit, 1 part almond oil and 4 parts rose water or distilled water on your scalp to keep dandruff at bay. Or:

Boil a mixture of 4-5 dried thyme and two cups of water for 10 minutes. When the mixture cools down, massage it on the scalp and leave it for half an hour. Wash it afterwards and see the results. You will have a dandruff-free head.

You can also soak ground fenugreek seeds overnight in water and massage the paste on the head, leaving it for a few minutes. Wash it afterwards using a mild shampoo.

You can also prepare a homemade mixture of 1 tablespoon fresh lemon juice with 100 grams witch hazel in 200ml of water and use it on washed hair. Applying the mixture several times is helpful in warding off the problem of dandruff.

If you wash your hair with warm apple cider vinegar, leaving it for 30-40 minutes and then rinsing it with plain water, you are sure to control dandruff positively. You have to continue this process regularly to stop its return. The smell of the vinegar does evaporate!

Try a mixture of olive oil and almond oil. Massage your scalp with the mixture and leave it for five minutes after you feel the burning sensation. Rinse properly and you should have a dandruff-free head.

Did you know the well-known pain killer aspirin, used for relieving aches, can serve you equally effectively to eliminate the problem of dandruff? Just crush and powder two aspirin tablets and add it to your shampoo. Leave the mixture on your scalp for two minutes. Rinse and wash properly to remove the aspirin particles completely from the scalp.

You can directly use Aloe Vera gel to remove excess dandruff. Apply the gel on your scalp 10-15 minutes before you plan to wash your hair. Regular use of the gel before shampooing will keep down the growth of dandruff.

These remedies take time to show a visible change but are effective for some people.

The best point concerning a home remedy is that you have many options and, if you think that a particular ingredient does not suit you, you can try an alternative. You should give each remedy at least a week before trying another.